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Slow-Cooked Barbecue Brisket with Homemade Barbecue Sauce: A Melt-in-Your-Mouth Recipe

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This Slow-Cooked Barbecue Brisket with Homemade Barbecue Sauce is fall-apart tender, rich with smoky flavor, and coated in a sweet, tangy, and savory homemade BBQ sauce. Whether cooked in the oven or slow cooker, it’s the ultimate comfort food for gatherings, meal prep, or weekend dinners.

Ingredients

  • 45 lbs beef brisket (whole or flat cut)
  • 1 large onion, sliced
  • 4 garlic cloves, minced
  • 2 tbsp smoked paprika
  • 3 tbsp brown sugar
  • 2 tsp salt
  • 1 tsp black pepper
  • 1 tsp chili powder or cayenne pepper (optional)
  • 1/4 cup apple cider vinegar
  • 2 tbsp tomato paste
  • 1 cup ketchup
  • 2 tbsp Worcestershire sauce
  • 1 tbsp Dijon mustard
  • 1/2 tsp liquid smoke (optional)
  • 2 tbsp olive oil
  • 1 cup water or beef broth

Instructions

  1. Mix brown sugar, smoked paprika, salt, pepper, and chili powder. Rub all over the brisket and let rest.
  2. In a saucepan, heat olive oil over medium heat. Sauté onions and garlic until soft.
  3. Stir in ketchup, tomato paste, apple cider vinegar, mustard, Worcestershire sauce, liquid smoke, and water or broth. Simmer for 10–15 minutes until thickened.
  4. Preheat oven to 300°F (150°C) or prepare slow cooker.
  5. Place brisket in a roasting pan or slow cooker, pour some sauce over the top, and scatter onions around.
  6. Cover tightly and cook for 5–6 hours in the oven or 8–10 hours on low in the slow cooker until fork-tender.
  7. Let brisket rest 15–20 minutes before slicing or shredding.
  8. Reheat with remaining sauce before serving.

Notes

  • Use chipotle peppers for a spicy, smoky variation.
  • Add honey or molasses for a sweeter BBQ sauce.
  • For quicker cooking, use a pressure cooker (Instant Pot).
  • Optional: sear brisket before cooking for added crust.
  • Resting before slicing keeps the meat juicy.

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