High Protein Creamy Chilli Chicken Enchiladas are one of my favorite ways to enjoy Mexican-inspired comfort food without skimping on nutrition. They’re packed with tender shredded chicken, a creamy chili-infused filling, and topped with a cheesy, protein-rich sauce that makes every bite indulgent yet wholesome. Perfect for a weeknight dinner or meal prep, these enchiladas are hearty, flavorful, and full of satisfying protein.

Why You’ll Love This Recipe

I love this recipe because it feels like comfort food but still fits into a balanced, high-protein diet. The creamy chili sauce brings just the right amount of spice, while the chicken and cheese keep things hearty and filling. It’s also a great make-ahead dish—I can prep the filling, roll up the tortillas, and bake when I’m ready. Plus, it freezes beautifully, so I always like to keep a batch on hand.

Ingredients

(Here’s a tip: Check out the full list of ingredients and measurements in the recipe card below.)

Cooked shredded chicken (breast or thighs, about 3 cups)
Whole wheat or high-protein tortillas
Plain Greek yogurt (or light sour cream)
Reduced-fat cream cheese (softened)
Shredded cheddar or Mexican blend cheese
Green chilies (diced, canned or fresh)
Red chili powder (adjust to spice level)
Garlic powder
Onion powder
Ground cumin
Smoked paprika
Salt and pepper
Enchilada sauce (red or green, depending on preference)
Fresh coriander/cilantro (for garnish)

Directions

Make the Filling: In a bowl, I combine shredded chicken, Greek yogurt, softened cream cheese, half the shredded cheese, diced green chilies, chili powder, garlic powder, onion powder, cumin, paprika, salt, and pepper. I mix until everything is creamy and well coated.
Assemble the Enchiladas: I spread a thin layer of enchilada sauce on the bottom of a greased baking dish. I spoon filling into each tortilla, roll it up tightly, and place seam-side down in the dish.
Top with Sauce and Cheese: Once all the tortillas are arranged, I pour the remaining enchilada sauce over the top and sprinkle with the rest of the cheese.
Bake: I cover with foil and bake at 375°F (190°C) for 20 minutes. Then I uncover and bake another 10 minutes until bubbly and golden.
Serve: I let the enchiladas rest for 5 minutes before serving and top with chopped cilantro for freshness.

Servings and timing

Servings: 6
Prep time: 15 minutes
Cook time: 30 minutes
Total time: 45 minutes

Variations

Sometimes I swap chicken for ground turkey or shredded rotisserie chicken when I’m short on time. If I want more heat, I add jalapeños or hot sauce to the filling. For extra nutrition, I like sneaking in spinach, black beans, or corn. I’ve also tried topping them with Greek yogurt-based ranch instead of enchilada sauce for a creamy twist.

Storage/Reheating

I store leftovers in the fridge for up to 4 days, covered tightly. They reheat best in the oven at 350°F until warmed through, though the microwave works for quick single servings. To freeze, I wrap the unbaked enchiladas tightly in foil and freeze for up to 2 months, then bake from frozen (adding about 15 extra minutes).

FAQs

Can I make these ahead of time?

Yes, I often assemble the enchiladas in the morning, refrigerate, and bake them at dinnertime. They hold up perfectly.

What’s the best tortilla to use?

I prefer whole wheat or high-protein tortillas for extra fiber and protein, but standard flour tortillas work just as well.

Can I make this gluten-free?

Yes, I just use gluten-free tortillas and double-check the enchilada sauce.

How spicy are these?

The heat level is flexible. I keep them mild by using just green chilies and a little chili powder, or make them fiery with jalapeños and extra cayenne.

Can I use low-fat cheese?

Yes, reduced-fat cheese works, though I like to use a mix for the best flavor and melt.

Conclusion

High Protein Creamy Chilli Chicken Enchiladas are the perfect mix of comfort food and smart nutrition. They’re creamy, cheesy, spicy, and loaded with satisfying protein to keep me full and energized. Whether I’m meal-prepping for the week or serving dinner to friends, this dish always delivers big flavor and comfort in every bite.